03-31-2013, 09:06 PM
Just a word of warning about the leg cramp pills, if you do use them make sure to not take more than is recommended. I am a pharmacist and am a little bored at work today. This is what it says on one of the drug references we use:
Both the FDA and the manufacturer warn against the off-label use of quinine for leg cramps. When used as approved by the FDA in the treatment of chloroquine-resistant malaria, a life-threatening illness, the risks associated with quinine use are justified. However, in the off-label use to prevent or treat nocturnal leg muscle cramps, the risks associated with quinine use, and the absence of evidence regarding its efficacy for such use, outweigh any potential benefit for this benign, self-limiting condition. Quinine has a narrow margin between an effective dose and a toxic dose. The dosing for FDA-approved use is supported by data to maximize the safety and efficacy of the product; the dosing for unapproved drugs and unapproved indications has not been reviewed and approved by FDA. Since 1969, FDA has received 665 reports of adverse events with serious outcomes associated with quinine use, including 93 deaths. Quinine-containing drugs are associated with serious side effects, severe hypersensitivity reactions, and the potential for serious drug interactions (see Contraindications/Precautions, Adverse Reactions, and Drug Interactions).
Ya'll are big boys so I'll leave it up to you decide if you want to use them or not. They can help, but again make sure not to use more than is recommended. I don't want to hear about dead float tubers from overdosing on quinine.
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Both the FDA and the manufacturer warn against the off-label use of quinine for leg cramps. When used as approved by the FDA in the treatment of chloroquine-resistant malaria, a life-threatening illness, the risks associated with quinine use are justified. However, in the off-label use to prevent or treat nocturnal leg muscle cramps, the risks associated with quinine use, and the absence of evidence regarding its efficacy for such use, outweigh any potential benefit for this benign, self-limiting condition. Quinine has a narrow margin between an effective dose and a toxic dose. The dosing for FDA-approved use is supported by data to maximize the safety and efficacy of the product; the dosing for unapproved drugs and unapproved indications has not been reviewed and approved by FDA. Since 1969, FDA has received 665 reports of adverse events with serious outcomes associated with quinine use, including 93 deaths. Quinine-containing drugs are associated with serious side effects, severe hypersensitivity reactions, and the potential for serious drug interactions (see Contraindications/Precautions, Adverse Reactions, and Drug Interactions).
Ya'll are big boys so I'll leave it up to you decide if you want to use them or not. They can help, but again make sure not to use more than is recommended. I don't want to hear about dead float tubers from overdosing on quinine.
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